This song is about coming to realization. That somebody that you're losing sleep over, constantly stressing over can "wreck your world". In this case he's warning you about "pretty girls". Coming to the realization that it's not worth it, and if you look hard enough you can "see right through" that pretty girl, and realize that anybody who would do you like that is not for you. "I know that you're not my kind". That what you have got to do to overcome those "broken-down-poorboy blues", that loneliness, worry and heartache is to "love someone new". The most important line of the song is, "I got me a worried mind, gonna find me a worried kind of girl, who's lonesome just like me.", and the end it gives you not a resolution as most sad songs don't, but hope and a goal in that line, and lets you know at the end that even when you've got nothing, you've got nothing to lose. A play on a Bob Dylan quote from the song "Like a Rolling Stone".