I think the song is saying "no more," "enough," and "cut the act." I see someone being told that they don't have to pretend to be someone's friend any longer, that they should just quit "faking" and go. A breaking point's been reached, and someone just doesn't want to play anymore games, listen to anymore lies, or (probably) be around a friend who doesn't honestly care about them. The part about the person's eyes lowering to floor means his (and I'm assuming it's a he) friend already knows he hasn't been honest. It's got to center around a friendship. And an end to some part or all of that friendship. Someone's being told to go and walk away. Hear how they're singing the song. Don't you think that breakthrough's been hard. (By the way, I know it's a tribute to the drummer who left the band. I tried to write about the heart, or the feelings, I got from the song.)